CD27 antibody - C-terminal region (ARP59093_P050) from Aviva Systems Biology

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CD27 antibody - C-terminal region (ARP59093_P050)

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The CD27 antibody - C-terminal region (ARP59093_P050) from Aviva Systems Biology is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The CD27 antibody - C-terminal region (ARP59093_P050) has been validated for the following applications: Western Blot.

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor